Lifestyle disorders & Probiotics

Not many are familiar with the term ‘Lifestyle disorder’. The simplest description of this term would be a disease that is caused due to the health-damaging choices made in day-to-day life. Most of the days are structured by taking into consideration comfort and rest. But these lifestyle choices pose a major threat to the general health.

According to a 2014 report, almost 26% of Indians between the ages of 30-70 are likely to succumb to lifestyle disorders such as heart disease and diabetes. A few of the diseases such as diabetes, sleep disorders, stress obesity, high cholesterol levels, cardiovascular diseases, and some forms of cancers can also be listed under the section of lifestyle diseases. In recent times, there is an increasing incidence of such diseases affecting even younger age groups. The changed living habits due to increasing sedentary lifestyles, employment, and competitive stress are the main culprits coming in the way of the golden rule of healthy living.

Nowadays improvements in health awareness, proper sanitation, and better medical facilities have helped to reduce the incidences of communicable and some vector borne diseases like cholera, polio, and malaria, but lifestyle disorders are escalating both in rural and urban areas. As we know lifestyle disorders are due to choices that people make in their life. The bright news is that most lifestyle diseases are reversible and also are preventable.

Causes:

The most common causes of lifestyle disorders are

• Over eating
• Consumption of unhealthy foods
• Over-dependence on processed foods,
• Energy drinks
• Use of artificial sweeteners and fast foods
• Sedentary living
• Drinking alcohol
• Stress
• Poor sleep patterns

One of the major examples of lifestyle disorder is Dyslipidemia which is also known as high cholesterol.

Recent studies have reported that high cholesterol is a condition which is present in 25-30% urban Indians and 15-20% in rural Indians. Dyslipidemia in India is high LDL cholesterol & low HDL cholesterol and high triglycerides. Lifestyle choices like a fatty diet, lack of exercise, unbalanced diet, consumption of alcohol, smoking, and certain health conditions can be responsible for altering the levels of both types of cholesterol leading to Hypercholesterolemia. Like several other present diseases, hypercholesterolemia does have a strong link to your family history and genetics. It may last from a few months to several years, depending on the response one gives to its onset. However, at this stage, tips and tentative solutions to treat the condition come in handy.

Tips to manage high cholesterol

There are three most necessary components for management of Dyslipidemia

• Appropriate Nutrition
• Self-care
• Medication

Nutrition focuses on foods that you should eat and avoid. In self-care,one should adopt regular exercise and healthy lifestyle activities. Current medications include the use of statins, however, long-term usage of statins is associated with side effects. Also, few of the population cannot tolerate statins and hence there is a hunt for alternative therapy which is significantly effective and also safe.

AB-Life^TM is a natural probiotic of human origin which is safe and effective to be used for conditions such as hypercholesterolemia. It is a blend of 3 strains of L. Plantarum. It is a patented probiotic formulation, and has been subjected to several in-vitro, and in-vivo as well as  clinical studies. AB-Life contains three probiotic strains with clinically proven effects on cholesterol and triglyceride levels.²

AB-Life^TM is available in the form of HPMC (veg) capsules and it is recommended to take 1 capsule per day for best results. It is proven to be capable of significantly reducing LDL (10%) and triglycerides (18%) through an innovative mechanism of action by modulation of the enterohepatic cholesterol cycle. Reported to be a safe and effective natural remedy to complement statin therapy, supports lifestyle intervention and improves compliance and adherence in a natural and very effective way.

Clinical study :

• Study design: A randomized, double-blind placebo-controlled study
• The aim of the study is to evaluate the efficacy of Lactobacillus plantarumstrains when combined with monacolin K in reducing blood cholesterol levels.
• Subjects: 39 adult patients having total cholesterol (TC) ≥200 mg/dL and recently stopped statin treatment because of intolerance.
• Subjects were given active and placebo once a day and were evaluated at baseline, 6, and 12 weeks.
• Results: change in LDL cholesterol and TC became significant compared to placebo upon adjusting for the baseline imbalance in hypercholesterolemia treatment. No adverse effects were reported during the study.
• Conclusion: The combination of 10 mg monacolin K and plantarum strains was well tolerated and achieved a statistically significant greater reduction in LDL-C and TC compared to placebo group.

Key features:

• Recognised as safe by USFDA, FDA and EFSA
• Patented probiotic formulation
• Clinically proven effective
• Available in more than 30 countries
• No interaction with other metabolic and cardiac therapies
• Safe and effective therapy.

 

References:

1. https://www.kokilabenhospital.com/blog/tips-to-prevent-lifestyle-diseases/
2. https://www.ab-biotics.com/probiotic-brazil-cholesterol/
3. Bosch M, Fuentes MC, Audivert S, Bonachera MA, Peiró S, Cuñé J. Lactobacillus plantarum CECT 7527, 7528 and 7529: probiotic candidates to reduce cholesterol levels. Journal of the Science of Food and Agriculture. 2014 Mar 15;94(4):803-9.
4. https://www.healthifyme.com/blog/manage-lifestyle-disorders/
5. Fuentes, M., Lajo, T., Carrión, J., & Cuñé, J. (2013). Cholesterol-lowering efficacy of Lactobacillus plantarum CECT 7527, 7528 and 7529 in hypercholesterolaemic adults. British Journal of Nutrition,109(10), 1866-1872. doi:10.1017/S000711451200373X
6. https://www.drlalsinghexpertise.com/blog/psychology/lifestyle-disorders-need-of-an-hour
7. https://www.healthifyme.com/blog/tips-to-manage-cholesterol/
8. Guerrero-Bonmatty R, Gil-Fernández G, Rodríguez-Velasco FJ, Espadaler-Mazo J. A combination of Lactoplantibacillus plantarum strains CECT7527, CECT7528, and CECT7529 plus monacolin K reduces blood cholesterol: Results from a randomized, double-blind, placebo-controlled study. Nutrients. 2021 Apr 6;13(4):1206.